ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2018, Vol. 49 ›› Issue (1): 1-9.doi: 10.11843/j.issn.0366-6964.2018.01.001

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The Prevalent History and Current Status of Porcine Reproductive and Respiratory Syndrome in China

GUO Zhen-hua1, CHEN Xin-xin1, LI Rui1, QIAO Song-lin1, GUO Jun-qing1, ZHANG Gai-ping1,2*   

  1. 1. Henan Provincial Key Laboratory of Animal Immunology/Key Laboratory of Animal Immunology of the Ministry of Agriculture, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China;
    2. Henan Agricultural University, Zhengzhou 450002, China
  • Received:2017-07-19 Online:2018-01-23 Published:2018-01-23

Abstract:

Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically important diseases in the world. It has been more than twenty years since the first report in China. The objective of this paper is to analyse the prevalent history and current status through a perspective of epidemiology, aiding to the prevention of PRRS virus (PRRSV). Both genotype 1 and genotype 2 PRRSV are prevalent in China. For genotype 2, majority of epidemic strains in the fields were clustered into four lineages (lineage 8, lineage 5, lineage 3 and lineage 1), among which lineage 8 (highly pathogenic PRRSV-like) and lineage 1 (NADC30-like) are dominant viruses. The genome homology between BJ-4 and VR2332 is 99.6%, which suggested that BJ-4 was probably imported from North America region. For genotype 1, all the isolated strains in China belong to subtype 1 and were detected in more than 9 provinces/regions. The Chinese isolated strains have highly conserved amino acid mutation sites on the GP5 and N protein compared with Lelystad virus.

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